{"id":3208,"date":"2024-06-10T14:43:37","date_gmt":"2024-06-10T12:43:37","guid":{"rendered":"https:\/\/www.bioclarma.com\/prodotto\/sensiquant-direct-cbfb-mhy11-mastermix-inv-16e\/"},"modified":"2024-12-17T09:39:25","modified_gmt":"2024-12-17T08:39:25","slug":"sensiquant-direct-cbfb-mhy11-mastermix-inv-16e","status":"publish","type":"product","link":"https:\/\/www.bioclarma.com\/en\/prodotto\/sensiquant-direct-cbfb-mhy11-mastermix-inv-16e\/","title":{"rendered":"SensiQuant Direct CBFB\/MHY11 MasterMix INV-16E"},"content":{"rendered":"<p>The <strong>SensiQuant Direct CBFB\/MYH11 MasterMix INV-16E (SQTd-046.E)<\/strong> kit represents a cutting-edge solution in the field of in vitro diagnostics, designed to deliver exceptional performance in two critical areas: <\/p>\n<ol>\n<li><strong>Qualitative detection:<\/strong> Accurately identifies the <strong>CBFB\/MYH11<\/strong> <strong>INV-16E<\/strong> translocation<strong>.<\/strong><\/li>\n<li><strong>Accurate quantification:<\/strong> Measures the transcript level of the <strong>CBFB\/MYH11<\/strong> <strong>INV-16E<\/strong><strong> translocation<\/strong> normalized to the <strong>ABL <\/strong>gene transcript.<\/li>\n<\/ol>\n<p> In samples of total RNA extracted from peripheral blood or bone marrow. &nbsp;<br \/><strong>FIELD OF APPLICATION<\/strong><br \/>The <strong>SensiQuant Direct CBFB\/MYH11 MasterMix INV-16E<\/strong> is essential for the identification and monitoring of Acute Myeloid Leukemia (<strong>AML<\/strong>). The product <strong>SQTd-046.E<\/strong> has been developed following the \u201c<em>Europe Against Cancer<\/em>\u201d (EAC) Guidelines (Gabert et al., Leukemia 2003) and meets all the most up-to-date international regulations (H. Dohner et al., Blood 2022).  &nbsp;<\/p>\n<p><strong>ASSOCIATED KITS AND ACCESSORIES<\/strong><br \/>To achieve optimal results, it is essential to use the <strong>SensiQuant Direct CBFB\/MYH11 MasterMix INV-16E (SQTd-046.E)<\/strong> in combination with:<br \/>&#8211; <strong>SensiQuant CBFB\/MYH11 Positive Control INV-16E<\/strong> (<strong>CTRL-046.E<\/strong>) for qualitative analysis<br \/>&#8211; <strong>SensiQuant CBFB\/MYH11 Standard INV-16E<\/strong> (<strong>STD-046.E<\/strong>) for quantitative analysis<br \/>With the <strong>SensiQuant Direct CBFB\/MYH11 MasterMix<\/strong>, we bring the precision and reliability of leukemia diagnosis to a higher level, providing industry specialists with high-quality tools for patient care.   &nbsp;<\/p>\n<p><strong>ADVANTAGES<\/strong><\/p>\n<ul>\n<li><strong>CE\/IVD<\/strong><\/li>\n<li><strong>&#8220;One Step&#8221; Technology<\/strong><\/li>\n<li><strong>Single plasmid <\/strong>(CBFB\/MYH11 and ABL)<\/li>\n<li><strong>Single Thermal Cycle<\/strong> for all products in the &#8220;<strong>SensiQuant DIRECT<\/strong>&#8221; line (analyzable in the same session)<\/li>\n<li><strong>Wide Range of Linearity <\/strong>(1,000,000 &#8211; 10 copies)<\/li>\n<li><strong>High Sensitivity<\/strong> (2 copies\/\u00b5l of sample)<\/li>\n<li><strong>High Specificity, Accuracy, <\/strong><strong>and Reproducibility<\/strong><\/li>\n<li><strong>High Stability<\/strong><\/li>\n<li><strong>Quick and Easy <\/strong>to Use<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Detection and Quantification of mRNA for the <strong>CBFB\/MYH11 translocation, INV-16 E<\/strong><\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"_gspb_post_css":""},"product_brand":[],"product_cat":[96,81],"product_tag":[],"class_list":["post-3208","product","type-product","status-publish","product_cat-cbfb-myh11-en","product_cat-oncohematology","first","instock","shipping-taxable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product\/3208","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/media?parent=3208"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_brand?post=3208"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_cat?post=3208"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_tag?post=3208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}