{"id":3227,"date":"2024-06-07T17:05:16","date_gmt":"2024-06-07T15:05:16","guid":{"rendered":"https:\/\/www.bioclarma.com\/prodotto\/sensiquant-direct-abl-mastermix\/"},"modified":"2024-06-07T17:05:16","modified_gmt":"2024-06-07T15:05:16","slug":"sensiquant-direct-abl-mastermix","status":"publish","type":"product","link":"https:\/\/www.bioclarma.com\/en\/prodotto\/sensiquant-direct-abl-mastermix\/","title":{"rendered":"SensiQuant Direct ABL MasterMix"},"content":{"rendered":"<p>The <strong>SensiQuant Direct ABL MasterMix<\/strong> product is available in two different packaging formats, identified by two product codes:<\/p>\n<ol>\n<li><strong>SQT-033<\/strong>: internal format, 72 duplicate determinations for ABL mRNA, totaling 144 determinations, including standards and controls.<\/li>\n<li><strong>SQT-033S<\/strong>: small format, 24 duplicate determinations for ABL mRNA, totaling 48 determinations, including standards and controls.<\/li>\n<\/ol>\n<p>The <strong>SensiQuant Direct ABL MasterMix<\/strong> kits are used for:<\/p>\n<ul>\n<li><strong>qualitative detection<\/strong> of the ABL gene transcript<\/li>\n<li><strong>quantitative<\/strong> <strong>measurement<\/strong> of the ABL gene transcript<\/li>\n<\/ul>\n<p>in <u><strong>total RNA samples extracted<\/strong><\/u> from peripheral blood or bone marrow, as well as from lymphomonocyte or leukocyte suspensions.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>FIELD OF APPLICATION<\/strong><\/p>\n<p>The <strong>SensiQuant Direct ABL<\/strong> <strong>MasterMix<\/strong> products are intended for the assessment of ABL transcript presence as a housekeeping gene in cases of chronic myeloid leukemia (CML), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and acute promyelocytic leukemia (APL). The <strong>SQTd-033\/SQTd-033S<\/strong> product has been developed in accordance with the \u201c<em>Europe Against Cancer<\/em>\u201d (EAC; Gabert et al., Leukemia 2003) guidelines and complies with all the most up-to-date international standards (Branford et al., Leukemia 2006; Hugues et al., Blood 2006).<\/p>\n<p>&nbsp;<\/p>\n<p><strong>ASSOCIATED KITS AND ACCESSORIES<\/strong><\/p>\n<p>The &#8220;<strong>SensiQuant Direct ABL MasterMix<\/strong>&#8221; products are to be used exclusively in conjunction with the &#8220;<strong>SensiQuant Direct MasterMix<\/strong>&#8221; kits for the translocation of interest and the corresponding &#8220;<strong>SensiQuant Standards<\/strong>&#8221; or &#8220;<strong>SensiQuant Positive Control<\/strong>&#8221; (see the following section on associated kits). With the <strong>SensiQuant Direct<\/strong> kits, we elevate the precision and reliability of leukemia diagnostics to a higher level, providing specialists with high-quality tools for patient care.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>ADVANTAGES<\/strong><\/p>\n<ul>\n<li><strong>CE\/IVD<\/strong><\/li>\n<li><strong>&#8220;One Step&#8221; Technology<\/strong><\/li>\n<li><strong>Single plasmid<\/strong> (translocation of interest and ABL)<\/li>\n<li><strong>Single Thermal Cycle<\/strong> for all products in the &#8220;<strong>SensiQuant DIRECT<\/strong>&#8221; line (analyzable in the same session)<\/li>\n<li><strong>Wide Range of Linearity <\/strong>(1,000,000 &#8211; 10 copies)<\/li>\n<li><strong>High Sensitivity<\/strong> (2 copies\/\u00b5l of sample)<\/li>\n<li><strong>High Specificity, Accuracy, <\/strong><strong>and Reproducibility<\/strong><\/li>\n<li><strong>High Stability<\/strong><\/li>\n<li><strong>Quick and Easy <\/strong>to Use<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Detection and Quantification of mRNA for the <strong>ABL<\/strong> gene transcript<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"_gspb_post_css":""},"product_brand":[],"product_cat":[96,81,97],"product_tag":[],"class_list":["post-3227","product","type-product","status-publish","product_cat-cbfb-myh11-en","product_cat-oncohematology","product_cat-pml-rara-en","first","instock","shipping-taxable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product\/3227","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:attachment":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/media?parent=3227"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_brand?post=3227"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_cat?post=3227"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_tag?post=3227"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}