{"id":97,"count":15,"description":"<p>The <strong>SensiQuant Direct PML\/RARa<\/strong> products are designed for the <strong>QUALITATIVE detection<\/strong> and <strong>QUANTITATIVE measurement<\/strong> of <strong>BCR1, BCR2, and BCR3<\/strong> transcripts in cases of Acute Promyelocytic Leukemia (APL).<\/p>\n\n<p>The product line includes:<\/p>\n<ul>\n    <li>SensiQuant <strong>Direct Master Mix<\/strong><\/li>\n    <li>SensiQuant <strong>Standard<\/strong> (from 10^5 to 10 copies)<\/li>\n    <li>SensiQuant <strong>Positive Control<\/strong><\/li>\n    <li><strong>Lyoset Reference<\/strong> (lyophilized cells, from 10% to 0.1% + Negative Control)<\/li>\n<\/ul>\n\n<strong>Main Breakpoints in the Cluster<\/strong>\n<p>\n    <strong>PML\/RARa t(15;17), variant BCR1<\/strong><br>\n    <strong>PML\/RARa t(15;17), variant BCR2<\/strong><br>\n    <strong>PML\/RARa t(15;17), variant BCR3<\/strong>\n<\/p>\n\n<strong>Application<\/strong>\n<ul>\n    <li><u>QUALITATIVE Analysis<\/u> = SensiQuant <strong>Direct Master Mix<\/strong> + SensiQuant <strong>Positive Control<\/strong><\/li>\n    <li><u>QUANTITATIVE Analysis<\/u> = SensiQuant <strong>Direct Master Mix<\/strong> + SensiQuant <strong>Standard<\/strong><\/li>\n<\/ul>\n\n<ul>\n    <li><strong><u>Lyoset Reference<\/u><\/strong>: Reference material consisting of ampoules containing lyophilized mixtures with known quantities of cells positive for the targeted translocation, diluted in negative cells. Essential for qualitative or quantitative performance assessment of translocation detection assays.<\/li>\n<\/ul>\n\n<strong>Benefits<\/strong>\n<ul>\n    <li><strong>One-Step Technology<\/strong><\/li>\n    <li><strong>Single plasmid<\/strong> of PML\/RARa and ABL<\/li>\n    <li><strong>Linear Range<\/strong> (1,000,000 to 10 copies PML\/RARa)<\/li>\n    <li><strong>Consistent Thermal Cycle<\/strong> across the <strong>SensiQuant DIRECT<\/strong> product line<\/li>\n    <li><strong>High ABL Copy Numbers<\/strong> (enhanced method sensitivity)<\/li>\n    <li><strong>High specificity, sensitivity, and accuracy<\/strong><\/li>\n    <li><strong>High reproducibility<\/strong> (intra- and inter-assay)<\/li>\n    <li><strong>Fast and easy to use<\/strong><\/li>\n    <li><strong>High stability<\/strong><\/li>\n    <li><strong>CE\/IVD marking<\/strong>*<\/li>\n<\/ul>\n\n<em>*except for LRF-045<\/em>","link":"https:\/\/www.bioclarma.com\/en\/product-category\/oncohematology\/pml-rara-en\/","name":"PML-RARa","slug":"pml-rara-en","taxonomy":"product_cat","parent":81,"meta":[],"menu_order":0,"acf":[],"_links":{"self":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_cat\/97","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_cat"}],"about":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/taxonomies\/product_cat"}],"up":[{"embeddable":true,"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product_cat\/81"}],"wp:post_type":[{"href":"https:\/\/www.bioclarma.com\/en\/wp-json\/wp\/v2\/product?product_cat=97"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}