SensiQuant Direct CBFB/MHY11 MasterMix INV-16E

The SensiQuant Direct CBFB/MYH11 MasterMix INV-16E (SQTd-046.E) kit represents a cutting-edge solution in the field of in vitro diagnostics, designed to deliver exceptional performance in two critical areas:

1. Qualitative detection: Accurately identifies the CBFB/MYH11 INV-16E translocation.
2. Accurate quantification: Measures the transcript level of the CBFB/MYH11 INV-16E translocation normalized to the ABL gene transcript.

In samples of total RNA extracted from peripheral blood or bone marrow.  
FIELD OF APPLICATION
The SensiQuant Direct CBFB/MYH11 MasterMix INV-16E is essential for the identification and monitoring of Acute Myeloid Leukemia (AML). The product SQTd-046.E has been developed following the “Europe Against Cancer” (EAC) Guidelines (Gabert et al., Leukemia 2003) and meets all the most up-to-date international regulations (H. Dohner et al., Blood 2022).  

ASSOCIATED KITS AND ACCESSORIES
To achieve optimal results, it is essential to use the SensiQuant Direct CBFB/MYH11 MasterMix INV-16E (SQTd-046.E) in combination with:
– SensiQuant CBFB/MYH11 Positive Control INV-16E (CTRL-046.E) for qualitative analysis
– SensiQuant CBFB/MYH11 Standard INV-16E (STD-046.E) for quantitative analysis
With the SensiQuant Direct CBFB/MYH11 MasterMix, we bring the precision and reliability of leukemia diagnosis to a higher level, providing industry specialists with high-quality tools for patient care.  

ADVANTAGES

• CE/IVD
• “One Step” Technology
• Single plasmid (CBFB/MYH11 and ABL)
• Single Thermal Cycle for all products in the “SensiQuant DIRECT” line (analyzable in the same session)
• Wide Range of Linearity (1,000,000 – 10 copies)
• High Sensitivity (2 copies/µl of sample)
• High Specificity, Accuracy, and Reproducibility
• High Stability
• Quick and Easy to Use